AI-Powered Organ Coordination

Every Organ.
Declared. Matched. Life-Saved.

GlobeOrgan is an AI-augmented, blockchain-anchored global platform that transforms organ donation from reactive post-mortem consent to proactive, informed pre-mortem declaration — multiplying the global organ supply while honouring every donor's dignity and autonomy.

60-Second Organ Matching
Blockchain Anchored
Apache 2.0 Open Source
GlobeOrgan Global Transplant Coordination Platform
🫀 The Crisis

The Organ Gap Is a Consent Problem

Globally, fewer than 30% of families consent to organ donation when asked for the first time at a critically ill patient's bedside. But when individuals have made an informed, voluntary pre-mortem declaration, family acceptance rises to over 90%. GlobeOrgan shifts the paradigm from reactive to proactive.

Predictive Health AI Engine for Organ Donation
Most Transformative Capability

Predictive Health Intelligence Engine

Over 3–5 years of longitudinal health data, the AI identifies patients whose trajectories indicate elevated probability of critical deterioration. Patients are engaged sensitively through their treating physician — never directly by the platform.

🧬

Organ-Specific Classifiers

Separate models for kidney (CKD→ESRD), liver (cirrhosis), heart failure, lung failure, and multi-organ failure.

📊

SHAP Explainability

Every AI output accompanied by SHAP values identifying top contributing features. No black-box decisions.

🔐

Federated Learning

Raw patient data never leaves the hospital. Only model weight updates transmitted with differential privacy.

Organ Donation Declaration Workflow
Legal Cornerstone

Blockchain-Anchored Declaration System

Every declaration is cryptographically anchored to Hyperledger Fabric — a permissioned blockchain operated by participating health ministries, WHO, and the platform. Tamper-evident, legally non-repudiable, and verifiable by any authorised party.

📋

Declaration Types

Full donation (all organs), selective (specific organs), exclusion-based, and conditional declarations supported.

👤

Guardian Management

Nominated guardian completes a mandatory 20-minute legal briefing. Role is to facilitate, never to override.

🔄

Annual Reaffirmation

Mandatory yearly review. Declarations not reaffirmed in 24 months flagged as Pending Review.

6-Stage Organ Matching Engine
Medically Critical Component

6-Stage Organ Matching Engine

Produces a ranked, medically valid, legally compliant allocation list within 60 seconds of organ availability. The system automatically identifies recipients from the waiting list database and hospital records — no manual selection, no human bias.

🚫

Stage 1: Hard Exclusions

Eliminate ABO-incompatible and DSA-positive crossmatch recipients. Absolute contraindications — no exceptions.

🚨

Stage 2: Medical Urgency

MELD ≥35 for liver, UNOS Status 1A/1B for heart/lung. Life-or-death patients ranked first automatically.

🧬

Stage 3: HLA Compatibility

0–6 antigen mismatch scoring. Zero-mismatch kidneys receive mandatory national first-priority allocation.

📍

Stage 4: Cold Ischaemia Logistics

Heart: 4–6 hrs, Kidney: 24–36 hrs, Liver: 8–12 hrs. Transport time vs. viability window validated in real-time.

🚨 Emergency & Anti-Bypass Safeguards

Tamper-Proof Allocation System

The system cannot be influenced, overridden, or bypassed for the misuse of organ transportation. Every allocation decision is algorithm-driven, multi-authority-approved, and immutably logged.

🚨

Emergency Life-or-Death Protocol

When a patient faces imminent death without transplant (Status 1A), the system triggers a Special Emergency Request requiring triple-authority approval: the treating hospital, the patient's transplant coordinator, and the government authority (NOTTO in India / UNOS in USA). No single entity can unilaterally approve.

🔒

Algorithm-Only Allocation

No human operator can manually override the ranked recipient list. The matching engine uses objective, data-driven medical criteria only — blood type, HLA compatibility, MELD/PELD scores, urgency status, and waiting time. Personal, social, or economic factors play zero role.

📋

Immutable Audit Trail (25 Years)

Every allocation decision, every status change, every approval/rejection is logged to an immutable audit store with actor identity, timestamp, and before/after values. Audit logs are preserved for 25 years per medico-legal requirements. Any anomaly triggers automatic ethics committee notification.

⚖️

Istanbul Declaration Compliance

Zero monetary value attached to any organ. Any attempt to attach financial terms is a platform violation triggering immediate suspension. Cross-border transfers require health ministry letter, diplomatic clearance, and INTERPOL notification for trafficking risk cases.

End-to-End

From Organ Availability to Transplant Completion

🫀

Organ Available

Registered within minutes of certification

🤖

AI Match

6-stage algorithm in under 60 seconds

Multi-Auth

Hospital + Patient + Govt authority approval

🚗

Green Corridor

Traffic-cleared route with GPS tracking

🏥

Transplant

Surgery within viability window

📋

Outcome

Full chain-of-custody audit logged

Deployment

Global Rollout Roadmap

Phase 1 (Mo 1–6)

India MVP

Full NOTTO/SOTTO/ROTTO integration. Declaration module. Guardian management. 50 transplant centres onboarded.

Phase 2 (Mo 7–12)

South Asia + Middle East

Sri Lanka, Bangladesh, Nepal, Saudi Arabia, UAE, Kuwait. Country-specific legal modules.

Phase 3 (Year 2)

EU, UK, USA, Australia

EU Directive 2010/53/EU. UNOS/OPTN integration. UK opt-out system. Federated AI deployment.

Phase 4 (Year 3)

Global

All nations with organ donation legislation. Rare organ global registry. WHO partnership. Cross-border coordination.

🔍 Fact-Check & Data Integrity Report

All claims cross-referenced against GlobeOrgan Requirements Documentation v1.0, WHO Guiding Principles, THOA 1994, and UNOS/OPTN policies:

✅ VERIFIED — HLA Matching Standards

HLA-A, B, C (Class I) and HLA-DR, DQ, DP (Class II) typing, 0–6 mismatch scoring, PRA/DSA virtual crossmatch — all confirmed against Transplantation Society (TTS) standards.

✅ VERIFIED — Indian THOA 1994 Compliance

Brain-stem death recognition, Authorisation Committee for non-near-relatives, NOTTO/SOTTO/ROTTO allocation hierarchy, and commercial trade prohibition — all correctly referenced per the Act.

✅ VERIFIED — Anti-Trafficking Controls

Istanbul Declaration alignment, WHO Guiding Principle 5 (prohibition of organ commercialisation), INTERPOL notification for cross-border trafficking risk — all confirmed.

⚠️ CAUTION — Success Metrics Are Targets

Year 1 metrics (500+ centres, 50K+ declarations, 100K+ health profiles) are aspirational targets. Platform is in v1.0 pre-launch phase as of May 2026.

✅ VERIFIED — Organ Viability Windows

Heart 4–6 hrs, Liver 8–12 hrs, Kidney 24–36 hrs cold ischaemia times are consistent with published transplantation literature and ASTS guidelines.

✅ VERIFIED — Consent Statistics

30% family consent for first-time bedside requests and 90%+ acceptance with pre-mortem declarations are consistent with published research in transplantation ethics literature.

GlobeOrgan — No Life Lost for Want of an Organ

AI-powered. Blockchain-secured. Legally compliant. Tamper-proof. Join the movement to transform organ donation worldwide.

🤝 Partner With Us 🩸 GlobeBlood Platform